This study investigates how a comparison between the Catholic theologian Edward Schillebeeckx's controversial reading of Thomist philosophy and the Tibetan Buddhist Gendun Chopel's challenge to the standard Geluk teaching of Tsongkhapa's Madhyamaka philosophy might assist in rethinking conceptions of religious knowledge.Utilizing a wide variety of methodical approaches to establish an imaginary dialogue between these two thinkers, this comparison remains embodied in the thought and praxis of actual individuals, and yet still firmly embedded within the conversations and trajectories of their broader religious traditions.